首页

HOME

机构简介

INTRODUCTION

科研骨干

SPECIALISTS

科研成果

ACHEVEMENTS

发展方向

development direction

寻求合作

EDUCATION ADVISORY

教育咨询

COOPERATION

党员天地

COMMUNIST

联系我们

CONTACT

 
 
   
您的位置:首页 >> 科研成果    
 

研究项目(七)study projects-7

  访问量:[944]  发布日期:[2016-11-25 16:27:42]

研究项目(七)study projects-7

五、生殖毒性试验
Reproductive Toxicity Study

1、生育力与早期胚胎发育毒性试验(一般生殖毒性试验,即Ⅰ段生殖毒性试验)
Fertility and Early Embryo Developmental Toxicity Study

(1)注射用灯盏花素SD大鼠静脉给药生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity test of erigeron injection by intravenous injection in SD rats

(2)雄地那非SD大鼠灌胃生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity test of Xiongdinafei by intragastric administration in SD rats

(3)红花如意丸SD大鼠灌胃药生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity test of Honghua Ruyi Pill by intragastric administration in SD rats

(4)ZY-Z001 SD大鼠灌胃生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity test of ZY-001 by intragastric administration in SD rats

(5)保妇康栓SD大鼠阴道给药生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity test of suppository of baofukang by vaginal administration in SD rats

(6)YF-49-92.MLS SD大鼠灌胃生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity test of YF-49-92.MLS by intragastric administration in SD rats

(7)美他卡韦大鼠灌胃生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity study on metacavir by intragastric administration in rats

(8)TY501大鼠灌胃生育力与早期胚胎发育毒性试验
Fertility and early embryo developmental toxicity study on TY501 by intragastric administration in rats

(9)ALS-3 SD大鼠灌胃(ig)生育力与早期胚胎发育毒性试验(Ⅰ段)
Fertility and early embryo developmental toxicity study on TY501 by intragastric administration in SD rats.

(10)聚乙二醇重组人生长激素SD大鼠皮下注射(sc)一般生殖毒性试验
General reproductive toxicity study on PEG-hGH by subcutaneous injection in SD rats

(11)吗啉硝唑SD大鼠静脉注射(iv)一般生殖毒性试验
General reproductive toxicity study on morpholine ornidazole by intravenous injection in SD rats

(12)长效干扰素SD大鼠皮下注射(sc)一般生殖毒性试验
General reproductive toxicity study on Long-acting interferon by subcutaneous injection in SD rats

(13)甲磺酸西那沙星注射液SD大鼠静脉注射(iv)一般生殖毒性试验
General reproductive toxicity study on sinafloxacin mesilate by intravenous injection in SD rats

(14)阿地福韦双特戊酰氧基甲酯SD大鼠灌胃(ig)一般生殖毒性试验
General reproductive toxicity study on adefovir dipivixil by intragastric administration in SD rats

(15)(-)黄皮酰胺SD大鼠灌胃(ig)一般生殖毒性试验
General reproductive toxicity study on (-)-clausenamide by intragastric administration in SD rats.

2、胚胎-胎仔发育毒性试验(致畸敏感期毒性试验,即Ⅱ段生殖毒性试验)
Embryo-foetus Developmental Toxicity Study

(1)利用SD大鼠进行的研究
Study with SD rats

雄地那非SD大鼠灌胃胚胎-胎仔发育毒性生殖毒性试验
Embryo-foetus developmental toxicity test of Honghua Ruyi Pill by intragastric administration in SD rats

红花如意丸SD大鼠灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of suppository of baofukang by vaginal administration in SD rats

ZY-Z001 SD大鼠灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of ZY-001 by intragastric administration in SD rats

保妇康栓SD大鼠阴道给药胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of suppository of baofukang by vaginal administration in SD rats

YF-49-92.MLS SD大鼠灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of YF-49-92.MLS by intragastric administration in SD rats

TY501大鼠灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of TY501 by intragastric administration in rats

注射用头孢他美钠 SD大鼠静脉给药(iv)胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity study on cefetamet sodium injection by intravenous administration in SD rats

聚乙二醇重组人生长激素SD大鼠皮下注射(sc)致畸敏感期毒性试验
Teratogenicity study on PEG-hGH by subcutaneous injection in SD rats

黄芪甲苷致SD大鼠静脉注射(iv)致畸敏感期毒性试验
Teratogenicity study on astragaloside by intravenous injection in SD rats

消避灵阴道栓SD大鼠阴道给药致畸敏感期毒性试验
Teratogenicity study on Xiaobiling pessary by vaginal administration in SD rats

长效干扰素SD大鼠皮下注射(sc)致畸敏感期毒性试验
Teratogenicity study on Long-acting interferon by subcutaneous injection in SD rats

聚乙二醇化天花粉蛋白SD大鼠静脉注射(iv)致畸敏感期毒性试验
Teratogenicity study on PEG-trichosanthin by intravenous injection in SD rats

PEG生长激素SD大鼠皮下注射(sc)致畸敏感期毒性试验
Teratogenicity study on PEG-GH by subcutaneous injection in SD rats

AWA静脉注射液SD大鼠静脉注射(iv)致畸敏感期毒性试验 
Teratogenicity study on AWA injection by intravenous injection in SD rats

阿地福韦双特戊酰氧基甲酯SD大鼠灌胃(ig)致畸敏感期毒性试验
Teratogenicity study on adefovir dipivixil by intragastric administration in SD rats

(-)黄皮酰胺SD大鼠灌胃(ig)致畸敏感期毒性试验
Teratogenicity study on (-)-clausenamide by intragastric administration in SD rats

(2)利用新西兰兔进行的研究
Study with new zealand rabbits

银杏二萜内酯葡胺注射液静脉注射兔胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of ginkgolide meglumine injection by intravenous injection in New Zealand rabbits

雄地那非新西兰兔灌胃胚胎-胎仔发育毒性生殖毒性试验
Embryo-foetus developmental toxicity test of Xiongdinafei by intragastric administration in New Zealand rabbits

重组红细胞生成刺激蛋白皮下注射兔胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of ZY-001 by intragastric administration in rabbits

ZY-Z001 兔灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of suppository of baofukang by vaginal administration in rabbits

保妇康栓兔阴道给药胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity test of metacavir by intragastric administration in rabbits

美他卡韦兔灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity study on metacavir by intragastric administration in rabbits

TY501兔灌胃胚胎-胎仔发育毒性试验
Embryo-foetus developmental toxicity study on TY501 by intragastric administration in rabbits

阿可拉定兔灌胃胚胎-胎仔发育毒性试验(Ⅱ段)
Embryo-foetus developmental toxicity study on IC-162 by intragastric administration in rabbits

ALS-3新西兰兔灌胃(ig)胚胎-胎仔发育毒性试验(Ⅱ段)
Embryo-foetus developmental toxicity study on ALS-3 by intragastric administration in New Zealand rabbits

T-8新西兰兔灌胃(ig)胚胎-胎仔发育毒性试验(Ⅱ段)
Embryo-foetus developmental toxicity study on T-8 by intragastric administration in New Zealand rabbits

PEX-168新西兰兔皮下注射(sc)致畸敏感期毒性试验
Embryo-foetus developmental toxicity study on PEX-168 by subcutaneous injection in New Zealand rabbits

吗啉硝唑新西兰兔静脉注射(iv)致畸敏感期毒性试验
Embryo-foetus developmental toxicity study on morpholine ornidazole by intravenous injection in New Zealand rabbits

甲磺酸西那沙星注射液新西兰兔静脉注射(iv)致畸敏感期毒性试验
Embryo-foetus developmental toxicity study on sinafloxacin mesilate injection by intravenous injection in New Zealand rabbits

3、围产期毒性试验(即Ⅲ段生殖毒性试验)
Perinatal toxicity study

(1)银杏二萜内酯葡胺注射液静脉注射大鼠围产期毒性试验
Perinatal toxicity test of ginkgolide meglumine injection by intragastric administration in SD rats

(2)ZY-Z001 SD大鼠灌胃围产期毒性试验
Perinatal toxicity test of ZY-001 by intragastric administration in SD rats

(3)保妇康栓SD大鼠阴道给药围产期毒性试验
Perinatal toxicity test of suppository of baofukang by vaginal administration in SD rats

(4)ALS-3 SD大鼠灌胃(ig)经口围产期生殖毒性试验(Ⅲ段)
Perinatal toxicity study on ALS-3 by intragastric administration in SD rats

(5)聚乙二醇重组人生长激素SD大鼠皮下注射(sc)围产期毒性试验
Perinatal toxicity study on PEG-hGH by subcutaneous injection in SD rats

(6)吗啉硝唑SD大鼠静脉注射(iv)围产期毒性试验
Perinatal toxicity study on morpholine ornidazole by intravenous injection in SD rats

(7)长效干扰素SD大鼠皮下注射(sc)围产期毒性试验
Perinatal toxicity study on Long-acting interferon by subcutaneous injection in SD rats

(8)甲磺酸西那沙星注射液SD大鼠静脉注射(iv)围产期毒性试验
Perinatal toxicity study on sinafloxacin mesilate injection by intravenous injection in SD rats

(9)(-)黄皮酰胺SD大鼠灌胃(ig)围产期毒性试验
Perinatal toxicity study on (-)-clausenamide by intragastric administration in SD rats

(10)阿地福韦双特戊酰氧基甲酯SD大鼠灌胃(ig)围产期毒性试验
Perinatal toxicity study on adefovir dipivixil by intragastric administration in SD rats


 

CopyRight© 1998-2019 All Right Reserved. 上海市计划生育科学研究所(生育调节药物毒理检测中心)  联系电话:021-64043044 或 64229909(办公室)
电子信箱:sunzy64@163.com  传 真:021-64438949 邮编:200032 地址:上海市徐汇区斜土路2140号   沪ICP备09020136号