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研究项目(九)study projects-9

  访问量:[636]  发布日期:[2016-11-25 15:49:42]

研究项目(九)study projects-9

八、局部刺激性试验
Local Irritation Test

1、血管刺激试验
Vascular Stimulation Test

(1)盐酸右美托咪定注射液兔静脉给药局部(血管)毒性试验
Local (vascular) irritation test of dexmedetomidine hydrochloride injection by intravenous administration in rabbits

(2)NCP4 SD大鼠和Beagle犬血管刺激试验
Vascular stimulation test of NCP4 in SD rats and Beagle dogs

(3)注射用灯盏花素Beagle犬3个月静脉给药局部(血管)刺激试验
Local (vascular) irritation test of erigeron injection by intravenous administration in beagle dogs for three months

(4)注射用灯盏花素 SD大鼠3个月静脉给药局部(血管)刺激试验
Local (vascular) irritation test of erigeron injection by intravenous administration in SD rats for three months

(5)碘帕醇注射液兔静脉给药局部(血管)刺激试验
Local (vascular) irritation test of iopamidol injection by intravenous administration in rabbits

(6)碘化油乙酯注射液兔静脉给药局部(血管)刺激试验
Local (vascular) irritation test of iodinate oil injection by intravenous administration in rabbits

(7)注射用头孢他美钠Beagle犬1个月静脉给药(iv)血管刺激试验
Vascular stimulation test of cefetamet sodium injection by intravenous administration in beagle dogs for one month

(8)注射用头孢他美钠 SD大鼠1个月静脉给药(iv)血管刺激试验
Vascular stimulation test of cefetamet sodium injection by intravenous administration in SD rats for one month

(9)多西他赛脂质体新西兰兔耳缘静脉注射(iv)局部刺激性试验
Local irritation test of docetaxel liposomes by intravenous injection in New Zealand rabbits

(10)注射用黄豆苷元新西兰兔耳缘静脉注射(iv)局部刺激性试验
Local irritation test of daidzein by intravenous injection in New Zealand rabbits

(11)注射用多西他赛纳米粒的新西兰兔耳缘静脉注射(iv)局部刺激性试验
Local irritation test of docetaxel nanoparticles by intravenous injection in New Zealand rabbits

(12)重组抗CD20人鼠嵌合单克隆抗体食蟹猴静脉滴注(iv)局部刺激性试验
Local irritation test of recombinant human/mouse chimeric anti-CD20 monoclonal antibody by intravenous drip in cynomolgus macaques

(13)重组抗CD3人鼠嵌合单克隆抗体食蟹猴静脉注射(iv)局部刺激性试验
Local irritation test of recombinant human/mouse chimeric anti-CD3 monoclonal antibody by intravenous injection in cynomolgus macaques

(14)注射用脉络宁Beagle犬静脉注射(iv)局部刺激性试验
Local irritation test of Mailuoning injection by intravenous injection in beagle dogs

(15)重组抗Ig E人源化单克隆抗体食蟹猴静脉注射(iv)局部刺激性试验
Local irritation test of recombinant anti-IgE humanized monoclonal antibody by intravenous injection in cynomolgus macaques

(16)重组抗TNF人鼠嵌合化单克隆抗体食蟹猴静脉注射(iv)局部刺激性试验
Local irritation test of recombinant human/mouse chimeric anti-TNF monoclonal antibody by intravenous injection in cynomolgus macaques

(17)注射用冠心灵Beagle犬静脉注射(iv)局部刺激性试验
Local irritation test of Guanxinling injection by intravenous injection in beagle dogs

(18)注射用丹红Beagle犬静脉注射(iv)局部刺激性试验
Local irritation test of Danhong injection by intravenous injection in beagle dogs

(19)重组抗CD25人鼠嵌合化单克隆抗体食蟹猴静脉注射(iv)局部刺激性实验
Local irritation test of recombinant human/mouse chimeric anti-CD25 monoclonal antibody by intravenous injection in cynomolgus macaques

(20)聚乙二醇化天花粉蛋白新西兰兔耳缘静脉注射(iv)局部刺激性试验
Local irritation test of PEG-trichosanthin by intravenous injection in New Zealand rabbits

(21)AWA静脉注射液新西兰兔耳缘静脉注射(iv)局部刺激性试验
Local irritation test of AWA injection by intravenous injection in New Zealand rabbits

2、皮肤刺激试验
Skin Irritation Test

(1)盐酸右美托咪定注射液兔静脉给药局部(皮肤)毒性试验
Local (skin) irritation test of dexmedetomidine hydrochloride injection by intravenous administration in rabbits

(2)NCP4 SD大鼠和Beagle犬皮肤刺激试验
Skin irritation test of NCP4 in SD rats and Beagle dogs

(3)注射用重组人促卵泡激素食蟹猴皮下注射3个月长期毒性伴随局部刺激性试验
Local irritation test associated with chronic toxicity test of rhFSH injection by subcutaneous injection in cynomolgus macaques for three months

(4)重组人Ⅱ型肿瘤坏死因子受体—抗体融合蛋白注射液兔皮下注射局部刺激性试验
Local irritation test of rhTNFR:Fc injection by subcutaneous injection in rabbits

(5)喷昔洛韦乳膏兔多次面部给药局部(皮肤、口唇粘膜)刺激性试验
Local (skin, mucous membrane) irritation test of penciclovir cream by multiple dosing transderm delivery in rabbits

(6)重组人Ⅱ型肿瘤坏死因子受体—抗体融合蛋白注射液食蟹猴皮下注射局部刺激性试验
Local irritation test of rhTNFR:Fc injection by subcutaneous injection in cynomolgus macaques

(7)重组人生长激素注射液兔皮下多次给药局部刺激性试验
Local (skin) irritation test of rhGH injection by multiple dosing subcutaneous injection in rabbits

(8)注射用灯盏花素Beagle犬3个月静脉给药局部(皮肤)刺激试验
Local (skin) irritation test of erigeron injection by intravenous administration in beagle dogs for three months

(9)注射用灯盏花素 SD大鼠3个月静脉给药局部(皮肤)刺激试验
Local (skin) irritation test of erigeron injection by intravenous administration in SD rats for three months

(10)碘帕醇注射液兔静脉给药局部(皮肤)刺激试验
Local (skin) irritation test of iopamidol injection by intravenous administration in rabbits

(11)碘化油乙酯注射液兔静脉给药局部(皮肤)刺激试验
Local (skin) irritation test of iodinate oil injection by intravenous administration in rabbits

(12)注射用头孢他美钠Beagle犬1个月静脉给药(iv)皮肤刺激试验
Skin irritation test of cefetamet sodium injection by intravenous administration in beagle dogs for one month

(13)注射用头孢他美钠 SD大鼠1个月静脉给药(iv)皮肤刺激试验
Skin irritation test of cefetamet sodium injection by intravenous administration in SD rats for one month

(14)重组人表皮生长因子兔单次给药皮肤刺激试验
Skin irritation test of rhEGF of single dosing in rabbits

(15)重组人表皮生长因子兔多次给药皮肤刺激试验
Skin irritation test of rhEGF of multiple dosing in rabbits

(16)聚乙二醇化重组人干扰素α-2b SD大鼠皮下注射(sc)局部刺激性试验
Local irritation test of PEG-IFN-α-2b by subcutaneous injection in SD rats

(17)HGH SD大鼠皮下注射(sc)局部刺激性试验
Local irritation test of HGH by subcutaneous injection in SD rats

(18)聚乙二醇重组人生长激素食蟹猴皮下注射(sc)局部刺激性试验
Local irritation test of PEG-hGH by subcutaneous injection in cynomolgus macaques

(19)长效干扰素食蟹猴皮下注射(sc)局部刺激性试验
Local irritation test of long-acting interferon by subcutaneous injection in cynomolgus macaques

(20)长效干扰素SD大鼠皮下注射(sc)局部刺激性试验
Local irritation test of long-acting interferon by subcutaneous injection in SD rats

(21)长效孕三烯酮微球注射剂SD大鼠皮下注射(sc)局部刺激性试验
Local irritation test of long-acting gestrinone microspheres injection by subcutaneous injection in SD rats

(22)长效孕三烯酮微球注射剂食蟹猴皮下注射(sc)局部刺激性试验
Local irritation test of long-acting gestrinone microspheres injection by subcutaneous injection in cynomolgus macaques

(23)重组人干扰素α1β喷鼻剂新西兰兔皮肤给药局部刺激性试验
Local irritation test of rhIFN-α1β nasal spray by transderm delivery in New Zealand rabbits

3、腔道粘膜刺激试验
Cavitary Mucous Irritation Test

(1)妇康源阴道泡腾片兔多次阴道给药局部粘膜毒性试验
Local mucous irritation test of Fukangyuan vagina effervescent tablets by multiple dosing vaginal administration in rabbits

(2)妇炎消泡腾片兔多次阴道内外给药破损皮肤及粘膜刺激性试验
Abraded skin or mucous irritation test of fuyanxiao vagina effervescent tablets by multiple dosing internal and external vaginal administration in rabbits

(3)鬼臼毒素凝胶兔多次阴道内外给药局部(皮肤、粘膜)刺激性试验
Local irritation test of podophyllotoxin gel by multiple dosing vaginal administration in New Zealand rabbits

(4)乳杆菌阴道泡腾片ICR小鼠阴道给药局部刺激性试验
Local irritation test of lactobacillus acidphillus by vaginal administration in ICR mice

(5)复方西吡氯铵喷雾剂新西兰兔口腔给药局部刺激性试验
Local irritation test of compound cetylpyridinium chloride spray by buccal delivery in New Zealand rabbits

(6)消避灵阴道栓新西兰兔阴道给药局部刺激性试验
Local irritation test of Xiaobiling pessary by vaginal administration in New Zealand rabbits

(7)孕三烯酮阴道环新西兰兔阴道给药局部刺激性试验
Local irritation test of vaginal ring of Gestinone by vaginal administration in New Zealand rabbits

(8)澳玛阴道片新西兰兔阴道给药局部刺激性试验
Local irritation test of Aoma vaginal tablet by vaginal administration in New Zealand rabbits

(9)林氏咽宁散田鼠口腔喷雾局部刺激性试验
Local irritation test of Lin's yanning powder by oral spray in Microtus fortis

(10)硝酸异康唑阴道片新西兰兔阴道给药局部刺激性试验
Local irritation test of miconazole nitrate vaginal tablet by vaginal administration in New Zealand rabbits

(11)氨酚伪麻那敏口腔崩解片新西兰兔口腔给药局部刺激性试验
Local irritation test of acetaminophen pseudoephedrin hydrochloride and chlorpheniramine maleate orally disintegrating tablets by buccal delivery in New Zealand rabbits

(12)阿奇霉素新西兰兔口腔含服局部刺激性试验
Local irritation test of azithromycin by sublingual administration in New Zealand rabbits

(13)盐酸格拉司琼新西兰兔口腔含服局部刺激性试验
Local irritation test of granisetron hydrochloride by sublingual administration in New Zealand rabbits

(14)罗红霉素新西兰兔口腔含服局部刺激性试验
Local irritation test of roxithromycin by sublingual administration in New Zealand rabbits

(15)重组人干扰素α1β喷鼻剂新西兰兔鼻腔给药局部刺激性试验
Local irritation test of rhIFN-α1β nasal spray by intranasal administration in New Zealand rabbits

(16)重组人干扰素α1β喷鼻剂新西兰兔口腔给药局部刺激性试验
Local irritation test of rhIFN-α1β nasal spray by sublingual administration in New Zealand rabbits

(17)重组干扰素α1β滴鼻液新西兰兔鼻腔给药局部刺激性试验
Local irritation test of rhIFN-α1β nasal drops by intranasal administration in New Zealand rabbits

(18)重组r干扰素新西兰兔鼻腔给药局部刺激性试验
Local irritation test of recombinant IFNγ by intranasal administration in New Zealand rabbits

(19)葡萄糖酸锌滴鼻剂新西兰兔鼻腔给药局部刺激性试验
Local irritation test of zinc gluconate nasal drops by intranasal administration in New Zealand rabbits

4、眼刺激试验
Eye Irritation Test

(1)3H01凝胶剂兔眼刺激毒性试验
Eye irritation test of 3H01 gels in rabbits

(2)重组人表皮生长因子兔单次给药眼刺激试验
Eye irritation test of rhEGF by single-dose administration

(3)重组人表皮生长因子兔多次给药眼刺激试验
Eye irritation test of rhEGF by multi-dose administration

(4)复方醋酸氟米龙滴眼液新西兰兔滴眼给药局部刺激性试验
Local irritation test of compound acetate flurometholone eye drops by eye-drip administration in New Zealand rabbits

(5)国产Lata-noprost滴眼液新西兰兔滴眼给药局部刺激性试验
Local irritation test of Lata-noprost by eye-drip administration in New Zealand rabbits

5、肌肉刺激试验
Muscle Stimulation Test

(1)盐酸右美托咪定注射液兔静脉给药局部(肌肉)毒性试验
Local (muscle) irritation test of dexmedetomidine hydrochloride injection by intravenous administration in rabbits

(2)NCP4 SD大鼠和Beagle犬肌肉刺激试验
Muscle irritation test of NCP4 in SD rats and Beagle dogs

(3)注射用灯盏花素Beagle犬3个月静脉给药局部(肌肉)刺激试验
Local (muscle) irritation test of erigeron injection by intravenous administration in beagle dogs for three months

(4)注射用灯盏花素 SD大鼠3个月静脉给药局部(肌肉)刺激试验
Local (muscle) irritation test of erigeron injection by intravenous administration in SD rats for three months

(5)碘帕醇注射液兔静脉给药局部(肌肉)刺激试验
Local (muscle) irritation test of iopamidol injection by intravenous administration in rabbits

(6)碘化油乙酯注射液兔静脉给药局部(肌肉)刺激试验
Local (muscle) irritation test of iodinate oil injection by intravenous administration in rabbits

(7)注射用头孢他美钠 SD大鼠1个月静脉给药(iv)肌肉刺激试验
Muscle irritation test of cefetamet sodium injection by intravenous administration in SD rats for one month

(8)注射用头孢他美钠Beagle犬1个月静脉给药(iv)肌肉刺激试验
Muscle irritation test of cefetamet sodium injection by intravenous administration in beagle dogs for one month

6、溶血性试验
Hemolysis Test

(1)盐酸右美托咪定注射液兔溶血试验
Hemolysis test of dexmedetomidine hydrochloride injection in rabbits

(2)阿达木单抗兔溶血试验
Hemolysis test of adalimumab

(3)注射用重组人促卵泡激素兔溶血性试验
Hemolysis test of rhFSH

(4)NCP4兔溶血试验
Hemolysis test of NCP4

(5)注射用9-NC 兔溶血试验
Hemolysis test of 9-NC

(6)重组人Ⅱ型肿瘤坏死因子受体—抗体融合蛋白注射液溶血性试验
Hemolysis test of rhTNFR:Fc injection

(7)重组人生长激素注射液溶血性试验
Hemolysis test of rhGH injection

(8)注射用灯盏花素溶血性试验
Hemolysis test of erigeron injection

(9)碘帕醇注射液溶血性试验
Hemolysis test of iopamidol injection

(10)碘化油乙酯注射液溶血性试验
Hemolysis test of iodinate oil injection

(11)注射用头孢他美钠溶血性试验
Hemolysis test of cefetamet sodium injection

(12)聚乙二醇化重组人干扰素α-2b溶血性试验
Hemolysis test of PEG-IFN-α-2b

(13)多西他赛脂质体溶血性试验
Hemolysis test of docetaxel liposomes

(14)注射用黄豆苷元溶血性试验
Hemolysis test of daidzein injection

(15)注射用多西他赛纳米粒的溶血性试验
Hemolysis test of docetaxel nanoparticles

(16)重组抗CD3人鼠嵌合单克隆抗体溶血性试验
Hemolysis test of recombinant human/mouse chimeric anti-CD3 monoclonal antibody

(17)长效干扰素溶血性试验
Hemolysis test of long-acting interferon

(18)注射用脉络宁溶血性试验
Hemolysis test of Mailuoning injection

(19)重组抗Ig E人源化单克隆抗体溶血性试验
Hemolysis test of recombinant anti-IgE humanized monoclonal antibody

(20)注射用冠心灵溶血性试验
Hemolysis test of Guanxinling injection

(21)注射用丹红溶血性试验
Hemolysis test of Danhong injection

(22)聚乙二醇化天花粉蛋白溶血性试验
Hemolysis test of PEG-trichosanthin

(23)重组抗TNF人鼠嵌合化单克隆抗体溶血性试验
Hemolysis test of recombinant human/mouse chimeric anti-TNF monoclonal antibody

(24)重组抗CD25人鼠嵌合化单克隆抗体溶血性试验
Hemolysis test of recombinant human/mouse chimeric anti-CD25 monoclonal antibody

(25)AWA静脉注射液溶血性试验
Hemolysis test of AWA injection


 

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