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研究项目(四)study projects-4

  访问量:[1164]  发布日期:[2016-11-25 16:27:59]

研究项目(四)study projects-4

3.利用食蟹猴进行的研究
Study with cynomolgus macaques

(1)阿达木单抗食蟹猴皮下注射一般药理学试验
General pharmacology of adalimumab by subcutaneous injection in cynomolgus macaques

(2)注射用重组人促卵泡激素食蟹猴皮下注射一般药理学试验
General pharmacology of rhFSH injection by subcutaneous injection in cynomolgus macaques

(3)重组人Ⅱ型肿瘤坏死因子受体—抗体融合蛋白注射液食蟹猴一般药理学试验
General pharmacological study on rhTNFR:Fc injection by subcutaneous injection in cynomolgus macaques

(4)聚乙二醇化重组人干扰素α-2b食蟹猴皮下注射(sc)一般药理学试验
General pharmacological study on PEG-IFN-α-2b by subcutaneous injection in cynomolgus macaques

(5)HGH食蟹猴皮下注射(sc)一般药理学试验
General pharmacological study on HGH by subcutaneous injection in cynomolgus macaques

(6)重组抗CD20人鼠嵌合单克隆抗体食蟹猴静脉滴注(iv)一般药理学试验
General pharmacological study on recombinant human/mouse chimeric anti-CD20 monoclonal antibody by intravenous drip in cynomolgus macaques

(7)聚乙二醇重组人生长激素食蟹猴皮下注射(sc)一般药理学试验
General pharmacological study on PEG-hGH by subcutaneous injection in cynomolgus macaques

(8)重组抗CD3人鼠嵌合单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant human/mouse chimeric anti-CD3 monoclonal antibody by intravenous injection in cynomolgus macaques

(9)重组抗EGFR人鼠嵌合单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant human/mouse chimeric anti-EGFR monoclonal antibody by intravenous injection in cynomolgus macaques

(10)长效干扰素食蟹猴皮下注射(sc)一般药理学试验
General pharmacological study on long-acting interferon by subcutaneous injection in cynomolgus macaques

(11)重组SM-FL双功能抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant SM-FL bispecific antibody by intravenous injection in cynomolgus macaques

(12)重组抗Ig E人源化单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant anti-IgE humanized monoclonal antibody by intravenous injection in cynomolgus macaques

(13)重组抗CD52人源化单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant human/mouse chimeric anti-CD52 monoclonal antibody by intravenous injection in cynomolgus macaques

(14)重组抗TNF人鼠嵌合化单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant human/mouse chimeric anti-TNF monoclonal antibody by intravenous injection in cynomolgus macaques

(15)重组抗CD25人鼠嵌合化单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant human/mouse chimeric anti-CD25 monoclonal antibody by intravenous injection in cynomolgus macaques

(16)重组抗HER2人源化单克隆抗体食蟹猴静脉注射(iv)一般药理学试验
General pharmacological study on recombinant anti-HER2 humanized monoclonal antibody by intravenous injection in cynomolgus macaques

二、急性毒性试验
Acute Toxicity Test

1、利用ICR小鼠进行的研究
Study with ICR mice

(1)滋肾育胎丸小鼠灌胃急性毒性试验
Acute toxicity test of Zishengyutai Pill by intragastric administration in ICR mice

(2)复方坦洛新非那雄胺小鼠灌胃急性毒性试验
Acute toxicity test of Compound tamsolusin and finasteride by intragastric administration in ICR mice

(3)复方一枝蒿颗粒(儿童型)小鼠灌胃急性毒性试验
Acute toxicity test of Compound Artemisia Rupestris granules (for children) by intragastric administration in ICR mice

(4)NCP4小鼠静脉注射急性毒性试验
Acute toxicity test of NCP4 by intravenous injection in ICR mice

(5)注射用9-NC 小鼠静脉注射急性毒性试验
Acute toxicity test of 9-NC by intravenous injection in ICR mice

(6)YF-49-92.MLS小鼠灌胃急性毒性试验
Acute toxicity test of YF-49-92.MLS by intragastric administration in ICR mice

(7)YF-49-92.MLS 小鼠腹腔注射急性毒性试验
Acute toxicity test of YF-49-92.MLS by intraperitoneal injection in ICR mice

(8)乌骨藤总苷小鼠灌胃急性毒性试验
Acute toxicity test of the total glycosides of Marsdenia tenaccima by intragastric administration in ICR mice

(9)乌骨藤总苷小鼠腹腔注射急性毒性试验
Acute toxicity test of the total glycosides of Marsdenia tenaccima by intraperitoneal injection in ICR mice

(10)3H01凝胶剂小鼠滴眼急性毒性试验
Acute toxicity test of 3H01 gels by eye-drip administration in ICR mice

(11)3H01凝胶剂小鼠腹腔注射急性毒性试验
Acute toxicity test of 3H01 gels by intraperitoneal injection in ICR mice

(12)重组人Ⅱ型肿瘤坏死因子受体—抗体融合蛋白注射液小鼠静脉注射急性毒性试验
Acute toxicity study on rhTNFR:Fc injection by intravenous injection in mice

(13)重组人Ⅱ型肿瘤坏死因子受体—抗体融合蛋白注射液小鼠皮下注射急性毒性试验
Acute toxicity study on rhTNFR:Fc injection by subcutaneous injection in mice

(14)重组人生长激素注射液小鼠静脉给药急性毒性试验
Acute toxicity study on r-hGH injection by intravenous administration in mice

(15)重组人生长激素注射液小鼠皮下给药急性毒性试验
Acute toxicity study on r-hGH by subcutaneous injection in mice

(16)注射用灯盏花素小鼠静脉给药急性毒性试验
Acute toxicity study on erigeron injection by intravenous administration in mice

(17)注射用头孢他美钠小鼠静脉给药(iv)急性毒性试验
Acute toxicity study on cefetamet sodium injection by intravenous administration in mice

(18)重组人表皮生长因子小鼠灌胃(ig)急性毒性试验
Acute toxicity study on rhEGF by intragastric administration in mice

(19)重组人表皮生长因子小鼠静脉注射急性毒性试验
Acute toxicity study on rhEGF by intravenous administration in mice

(20)左旋泮托拉唑钠ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on (L)-pantoprazole sodium injection by intravenous administration in ICR mice

(21)聚乙二醇化重组人干扰素α-2b ICR小鼠皮下注射(sc)急性毒性试验
Acute toxicity study on PEG-IFN-α-2b by subcutaneous injection in ICR mice

(22)聚乙二醇化重组人干扰素α-2b ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on PEG-IFN-α-2b by intravenous injection in ICR mice

(23)抗凝系列药物ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on anticoagulant drugs by intragastric administration in ICR mice

(24)多西他赛注射液ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on docetaxel injection by intravenous injection in ICR mice

(25)多西他赛脂质体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on docetaxel liposomes by intravenous injection in ICR mice

(26)多西他赛纳米粒ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on docetaxel nanoparticles by intravenous injection in ICR mice

(27)消避灵阴道栓ICR小鼠阴道给药急性毒性试验
Acute toxicity study on Xiaobiling pessary by vaginal injection in ICR mice

(28)多西他赛脂质体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on docetaxel liposomes by intravenous injection in ICR mice

(29)注射用黄豆苷元ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on daidzein injection by intravenous injection in ICR mice

(30)注射用多西他赛纳米粒的ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on docetaxel nanoparticles injection by intravenous injection in ICR mice

(31)HGH ICR小鼠皮下注射(sc)急性毒性试验
Acute toxicity study on HGH by subcutaneous injection in ICR mice

(32)HGH ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on HGH by intravenous injection in ICR mice

(33)中药红藤颗粒剂ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on Chinese Herbs Sargentgloryvine Stem granules by intragastric administration in ICR mice

(34)中药红藤颗粒剂ICR小鼠腹腔(ip)急性毒性试验
Acute toxicity study on Chinese Herbs Sargentgloryvine Stem granules by intraperitoneal injection in ICR mice

(35)重组抗CD20人鼠嵌合单克隆抗体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on recombinant human/mouse chimeric anti-CD20 monoclonal antibody by intravenous injection in ICR mice

(36)聚乙二醇重组人生长激素ICR小鼠皮下注射(sc)急性毒性试验
Acute toxicity study on PEG-hGH by subcutaneous injection in ICR mice

(37)聚乙二醇重组人生长激素ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on PEG-hGH by intravenous injection in ICR mice

(38)新培菲康ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on new bifid triple viable by intragastric administration in ICR mice

(39)中药子宫肌瘤浸膏ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on Chinese Herbs Uterine Myoma extraction by intragastric administration in ICR mice

(40)中药子宫肌瘤浸膏ICR小鼠腹腔(ip)急性毒性试验
Acute toxicity study on Chinese Herbs Uterine Myoma extraction by intraperitoneal injection in ICR mice

(41)中药内异浸膏ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on Chinese Herbs Endometriosis extraction by intragastric administration in ICR mice

(42)中药内异浸膏ICR小鼠腹腔(ip.)急性毒性试验
Acute toxicity study on Chinese Herbs Endometriosis extraction by intraperitoneal injection in ICR mice

(43)重组抗CD3人鼠嵌合单克隆抗体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on recombinant human/mouse chimeric anti-CD3 monoclonal antibody by intravenous injection in ICR mice

(44)注射用脉络宁ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on Mailuoning injection by intravenous injection in ICR mice

(45)长效干扰素ICR小鼠皮下注射(sc)急性毒性试验
Acute toxicity study on long-acting interferon by subcutaneous injection in ICR mice

(46)长效干扰素ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on long-acting interferon by intravenous injection in ICR mice

(47)重组抗Ig E人源化单克隆抗体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on recombinant anti-IgE humanized monoclonal antibody by intravenous injection in ICR mice

(48)注射用冠心灵ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on Guanxinning injection by intravenous injection in ICR mice

(49)注射用丹红ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on Danhong injection by intravenous injection in ICR mice

(50)重组抗TNF人鼠嵌合化单克隆抗体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on recombinant human/mouse chimeric anti-TNF monoclonal antibody by intravenous injection in ICR mice

(51)聚乙二醇化天花粉蛋白ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on PEG-trichosanthin by intravenous injection in ICR mice

(52)重组抗CD25人鼠嵌合化单克隆抗体ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on recombinant human/mouse chimeric anti-CD25 monoclonal antibody by intravenous injection in ICR mice

(53)长效孕三烯酮微球注射剂ICR小鼠皮下注射(sc)急性毒性试验
Acute toxicity study on long-acting gestrinone microspheres injection by subcutaneous injection in ICR mice

(54)AHP ICR小鼠腹腔注射(ip)急性毒性试验
Acute toxicity study on AHP by intraperitoneal injection in ICR mice

(55)AHP ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on AHP by intragastric administration in ICR mice

(56)AWA静脉注射液ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on AWA injection by intravenous injection in ICR mice

(57)阿地福韦双特戊酰氧基甲酯ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on adefovir dipivixil by intragastric administration in ICR mice

(58)阿地福韦双特戊酰氧基甲酯ICR小鼠腹腔注射(ip)急性毒性试验
Acute toxicity study on adefovir dipivixil by intraperitoneal injection in ICR mice

(59)雷公藤多甙ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on Tripterygium Wifordii Hook f by intragastric administration in ICR mice

(60)CIK细胞注射液ICR小鼠静脉注射(iv)急性毒性试验
Acute toxicity study on CIK cell injection by intravenous injection in ICR mice

(61)枸缘酸舍曲林ICR小鼠灌胃(ig)急性毒性试验
Acute toxicity study on Sertraline Citrate by intragastric administration in ICR mice

(62)枸缘酸舍曲林ICR小鼠腹腔注射(ip)急性毒性试验
Acute toxicity study on Sertraline Citrate by intraperitoneal injection in ICR mice

(63)灯盏细辛酚ICR小鼠静脉注射(iv)急性试验
Acute toxicity study on phenylic compounds from Erigeron brev iscapus by intravenous injection in ICR mice

(64)葡萄糖酸锌滴鼻剂ICR小鼠鼻腔给药急性毒性试验
Acute toxicity study on zinc gluconate nasal drops by intranasal administration in ICR mice


 

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