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研究项目(五)study projects-5

  访问量:[600]  发布日期:[2016-11-25 16:27:54]

研究项目(五)study projects-5

2、利用SD大鼠进行的研究
Study with SD rats

(1)CT-1139 SD大鼠灌胃急性毒性研究
Acute toxicity test of CT-1139 by intragastric administration in SD rats

(2)CT-1139 SD大鼠腹腔注射急性毒性研究
Acute toxicity test of CT-1139 by intraperitoneal injection in SD rats

(3)雄地那非SD大鼠灌胃急性毒性试验
Acute toxicity test of Xiongdinafei by intragastric administration in SD rats

(4)雄地那非SD大鼠静脉注射急性毒性试验
Acute toxicity test of Xiongdinafei by intravenous administration in SD rats

(5)重组人干扰素α1β滴鼻液SD大鼠鼻腔给药急性毒性试验
Acute toxicity study on rhIFN-α1β nasal drops by intranasal administration in SD rats

(6)重组人干扰素α1β喷鼻剂SD大鼠鼻腔给药急性毒性试验
Acute toxicity study on rhIFN-α1β nasal spray by intranasal administration in SD rats

3、利用Beagle犬进行的研究
Study with Beagle dogs

(1)CT-1139 Beagle犬灌胃急性毒性研究
Acute toxicity test of CT-1139 by intragastric administration in Beagle dogs

(2)CT-1139 Beagle犬腹腔注射急性毒性研究
Acute toxicity test of CT-1139 by intraperitoneal injection in Beagle dogs

(3)雄地那非Beagle犬灌胃急性毒性试验
Acute toxicity test of Xiongdinafei by intragastric administration in Beagle dogs

(4)雄地那非Beagle犬静脉注射急性毒性试验
Acute toxicity test of Xiongdinafei by intravenous administration in Beagle dogs

(5)NCP4 Beagle犬静脉滴注急性毒性试验
Acute toxicity test of NCP4 by intravenous drip in Beagle dogs

(6)注射用9-NC Beagle犬静脉滴注急性毒性试验
Acute toxicity test of 9-NC by intravenous drip in Beagle dogs

(7)YF-49-92.MLS Beagle犬灌胃急性毒性试验
Acute toxicity test of YF-49-92.MLS by intragastric administration in Beagle dogs

(8)YF-49-92.MLS Beagle犬腹腔注射急性毒性试验
Acute toxicity test of YF-49-92.MLS by intraperitoneal injection in Beagle dogs

(9)乌骨藤总苷Beagle犬灌胃急性毒性试验
Acute toxicity test of the total glycosides of Marsdenia tenaccima by intragastric administration in Beagle dogs

(10)乌骨藤总苷Beagle犬腹腔注射急性毒性试验
Acute toxicity test of the total glycosides of Marsdenia tenaccima by intraperitoneal injection in Beagle dogs

(11)注射用灯盏花素Beagle犬静脉滴注急性毒性试验
Acute toxicity study on erigeron injection by intravenous drip in Beagle dogs

(12)注射用头孢他美钠Beagle犬静脉给药(iv)急性毒性试验
Acute toxicity study on cefetamet sodium injection by intravenous administration in Beagle dogs

(13)左旋泮托拉唑钠Beagle犬静脉注射(iv)急性毒性试验
Acute toxicity study on (L)-pantoprazole sodium injection by intravenous administration in Beagle dogs

(14)消避灵阴道栓Beagle犬阴道给药急性毒性试验
Acute toxicity study on Xiaobiling pessary by vaginal administration in Beagle dogs

4、利用食蟹猴进行的研究
Study with cynomolgus macaques

(1)阿达木单抗食蟹猴皮下注射急性毒性试验
Acute toxicity test of adalimumab by subcutaneous injection in cynomolgus macaques

(2)注射用重组人促卵泡激素食蟹猴皮下注射急性毒性试验
Acute toxicity test of rhFSH injection by subcutaneous injection in cynomolgus macaques

(3)聚乙二醇化重组人干扰素α-2b食蟹猴皮下注射(sc)急性毒性试验
Acute toxicity study on PEG-IFN-α-2b by subcutaneous injection in cynomolgus macaques

(4)聚乙二醇化重组人干扰素α-2b食蟹猴静脉注射(iv)急性毒性试验
Acute toxicity study on PEG-IFN-α-2b by intravenous injection in cynomolgus macaques

(5)重组抗CD20人鼠嵌合单克隆抗体食蟹猴静脉滴注(iv)急性毒性试验
Acute toxicity study on recombinant human/mouse chimeric anti-CD20 monoclonal antibody by intravenous drip in cynomolgus macaques

(6)重组抗Ig E人源化单克隆抗体食蟹猴静脉注射(iv)急性毒性试验
Acute toxicity study on recombinant anti-IgE humanized monoclonal antibody by intravenous injection in cynomolgus macaques

三、长期毒性试验
Chronic Toxicity Test

1、利用SD大鼠进行的研究
Study with SD rats

(1)CT-1139 SD大鼠灌胃1个月长期毒性试验
Chronic toxicity test of CT-1139 by intragastric administration in SD rats for one month

(2)小儿蒿芩抗感颗粒SD幼龄大鼠灌胃4周长期毒性试验
Chronic toxicity test of children haoqin kanggan granules by intragastric administration in child SD rats for four weeks

(3)雄地那非SD大鼠灌胃1个月长期毒性试验
Chronic toxicity test of Xiongdinafei by intragastric administration in SD rats for one month

(4)复方坦洛新非那雄胺大鼠灌胃6个月长期毒性试验
Chronic toxicity test of Compound tamsolusin and finasteride by intragastric administration in SD rats for six months

(5)复方一枝蒿颗粒(儿童型)大鼠灌胃一个月长期毒性试验
Chronic toxicity test of Compound Artemisia Rupestris granules (for children) by intragastric administration in SD rats for one month

(6)NCP4 SD大鼠1个月静脉注射长期毒性试验
Chronic toxicity test of NCP4 by intravenous injection in SD rats for one month

(7)YF-49-92.MLS SD大鼠1个月灌胃长期毒性试验
Chronic toxicity test of YF-49-92.MLS by intragastric administration in SD rats for one month

(8)乌骨藤总苷SD大鼠灌胃3个月长期毒性试验
Chronic toxicity test of the total glycosides of Marsdenia tenaccima by intragastric administration in SD rats for three months

(9)注射用灯盏花素 SD大鼠3个月静脉给药长期毒性试验
Chronic toxicity study on erigeron injection by intravenous administration in SD rats for three months

(10)注射用头孢他美钠 SD大鼠1个月静脉给药(iv)长期毒性试验
Chronic toxicity study on cefetamet sodium injection by intravenous administration in SD rats for one month

(11)左旋泮托拉唑钠SD大鼠静脉注射(iv)1个月长期毒性试验
Chronic toxicity study on (L)-pantoprazole sodium injection by intravenous injection in SD rats for one month

(12)聚乙二醇化重组人干扰素α-2b SD大鼠皮下注射(sc)长期毒性试验
Chronic toxicity study on PEG-IFN-α-2b by subcutaneous injection in SD rats

(13)消避灵阴道栓SD大鼠1个月阴道给药长期毒性试验
Chronic toxicity study on Xiaobiling pessary by vaginal administration in SD rats for one month

(14)多西他赛脂质体SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on docetaxel liposomes by intravenous injection in SD rats for three months

(15)注射用黄豆苷元SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on daidzein by intravenous injection in SD rats for three months

(16)HGH SD大鼠皮下注射(sc)3个月长期毒性试验
Chronic toxicity study on HGH by subcutaneous injection in SD rats for three months

(17)中药红藤颗粒剂SD大鼠灌胃(ig)长期毒性试验
Chronic toxicity study on Chinese Herbs Sargentgloryvine Stem granules by intragastric administration in SD rats

(18)聚乙二醇重组人生长激素SD大鼠皮下注射(sc)6个月长期毒性试验
Chronic toxicity study on PEG-hGH by subcutaneous injection in SD rats for six months

(19)中药子宫肌瘤浸膏SD大鼠灌胃(ig)长期毒性试验
Chronic toxicity study on Chinese Herbs Uterine Myoma extraction by intragastric administration in SD rats

(20)中药内异浸膏SD大鼠灌胃(ig)3个月长期毒性试验
Chronic toxicity study on Chinese Herbs Endometriosis extraction by intragastric administration in SD rats for three months

(21)注射用脉络宁SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on Mailuoning injection by intravenous injection in SD rats for three months

(22)MP513 SD大鼠灌胃(ig)1个月长期毒性试验
Chronic toxicity study on MP513 by intragastric administration in SD rats for one month

(23)长效干扰素SD大鼠皮下注射(sc)6个月长期毒性试验
Chronic toxicity study on long-acting interferon by subcutaneous injection in SD rats for six months

(24)注射用冠心灵SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on Guanxinning injection by intravenous injection in SD rats for three months

(25)注射用丹红SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on Danhong injection by intravenous injection in SD rats for three months

(26)聚乙二醇化天花粉蛋白SD大鼠静脉注射(iv)6个长期毒性试验
Chronic toxicity study on PEG-trichosanthin by intravenous injection in SD rats for six months

(27)长效孕三烯酮微球注射剂SD大鼠皮下注射(sc)6个月长期毒性试验
Chronic toxicity study on long-acting gestrinone microspheres injection by subcutaneous injection in SD rats for six months

(28)丹参多酚盐SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on salvianolate by intravenous injection in SD rats for three months

(29)AWA静脉注射液SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on AWA injection by intravenous injection in SD rats for three months

(30)阿地福韦双特戊酰氧基甲酯SD大鼠灌胃(ig)6个月长期毒性试验
Chronic toxicity study on adefovir dipivixil by intragastric administration in SD rats for six months

(31)灯盏细辛酚SD大鼠静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on phenylic compounds from Erigeron brev iscapus by intravenous injection in SD rats for three months

2、利用Beagle犬进行的研究
Study with Beagle dogs

(1)CT-1139 Beagle犬灌胃1个月长期毒性试验
Chronic toxicity test of CT-1139 by intragastric administration in Beagle dogs for one month

(2)雄地那非Beagle犬灌胃1个月长期毒性试验
Chronic toxicity test of Xiongdinafei by intragastric administration in Beagle dogs for one month

(3)复方坦洛新非那雄胺Beagle犬灌胃9个月长期毒性试验
Chronic toxicity test of Compound tamsolusin and finasteride by intragastric administration in Beagle dogs for nine months

(4)妇康源阴道泡腾片Beagle犬阴道给药1个月长期毒性试验
Chronic toxicity test of Fukangyuan vaginal effervescent tablets by vaginal administration in Beagle dogs for one month

(5)ZY-Z001 Beagle犬9个月口服长毒性试验
Chronic toxicity test of ZY-Z001 by oral administration in Beagle dogs for nine months

(6)NCP4 Beagle犬1个月静脉滴注长期毒性试验
Chronic toxicity test of NCP4 by intravenous drip in Beagle dogs for one month

(7)YF-49-92.MLS Beagle犬1个月灌胃长期毒性试验
Chronic toxicity test of YF-49-92.MLS by intragastric administration in Beagle dogs for one month

(8)乌骨藤总苷Beagle犬灌胃3个月长期毒性试验
Chronic toxicity test of the total glycosides of Marsdenia tenaccima by intragastric administration in Beagle dogs for three months

(9)龙胆总苷Beagle犬3个月灌胃长期毒性试验
Chronic toxicity test of the total glycosides of Radix Gentianae by intragastric administration in Beagle dogs for three months

(10)多西他赛前体脂质体Beagle犬1个月静脉给药长期毒性试验
Chronic toxicity study on docetaxel proliposomes by intravenous injection in Beagle dogs for one month

(11)注射用灯盏花素Beagle犬3个月静脉滴注长期毒性试验
Chronic toxicity study on erigeron injection by intravenous drip in Beagle dogs for three months

(12)注射用头孢他美钠Beagle犬1个月静脉给药(iv)长期毒性试验
Chronic toxicity study on cefetamet sodium injection by intravenous administration in Beagle dogs for one month

(13)注射用多西他赛纳米粒Beagle犬1个月静脉滴注(iv)长期毒性试验
Chronic toxicity study on nanoparticle-docetaxel injection by intravenous drip in Beagle dogs for one month

(14)左旋泮托拉唑钠Beagle犬静脉滴注(iv)1个月长期毒性试验
Chronic toxicity study on (L)-pantoprazole sodium injection by intravenous drip in Beagle dogs for one month

(15)重组人纽兰格林Beagle犬静脉滴注(iv)临床前毒理学研究
Preclinical toxicological study on recombinant Neuregulin by intravenous drip in Beagle dogs

(16)消避灵阴道栓Beagle犬1个月阴道给药长期毒性试验
Chronic toxicity study on Xiaobiling pessary by vaginal administration in Beagle dogs for one month

(17)多西他赛脂质体Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on docetaxel liposomes by intravenous injection in Beagle dogs for three months

(18)注射用黄豆苷元Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on daidzein injection by intravenous injection in Beagle dogs for three months

(19)注射用脉络宁Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on Mailuoning injection by intravenous injection in Beagle dogs for three months

(20)消避灵阴道栓Beagle犬阴道给药1个月长期毒性试验
Chronic toxicity study on Xiaobiling pessary by vaginal administration in Beagle dogs for one month

(21)注射用冠心灵Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on Guanxinning injection by intravenous injection in Beagle dogs for three months

(22)注射用丹红Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on Danhong injection by intravenous injection in Beagle dogs for three months

(23)丹参多酚盐Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on salvianolate by intravenous injection in Beagle dogs for three months

(24)AWA静脉注射Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on AWA injection by intravenous injection in Beagle dogs for three months

(25)抗肝炎病毒药阿地福韦双特戊酰氧基甲酯Beagle犬灌胃(ig)一般药理学试验
General pharmacology of adefovir dipivixil for treating hepatitis virus by intragastric administration in beagle dogs

(26)阿地福韦双特戊酰氧基甲酯Beagle犬灌胃(ig)9个月长期毒性试验
Chronic toxicity study on adefovir dipivixil by intragastric administration in Beagle dogs for nine months

(27)灯盏细辛酚Beagle犬静脉注射(iv)3个月长期毒性试验
Chronic toxicity study on phenylic compounds from Erigeron brev iscapus by intravenous injection in Beagle dogs for three months


 

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