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吴建辉,研究员,复旦大学硕士生导师

  访问量:[1111]  发布日期:[2016-11-24 18:50:52]

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吴建辉,药理学博士, 研究员,复旦大学硕士生导师


姓名:吴建辉,药理学博士, 研究员,复旦大学硕士生导师


电话:021-64438949


E-mail:wwjh_731@yahoo.com.cn


研究方向:前列腺疾病药理毒理学、男性生殖健康和新药临床前安全性评价


个人简介:

吴建辉,男,汉族,中共党员,19767月出生,江西省吉安市新干县人,药理学博士,研究员,复旦大学药学院硕士研究生导师。现任上海市计划生育科学研究所药理毒理学研究室(中国生育调节药物毒理检测中心)副主任及党支部书记。研究方向为前列腺疾病药理毒理学、男性生殖健康及新药临床前安全性评价,重点关注领域为前列腺增生发生机制及治疗药物研发。主持国家自然科学基金项目《环境内分泌干扰物双酚A与前列腺增生关系探讨》、上海市人才发展资金项目《具雌激素活性内分泌干扰物与前列腺增生的关系及机制探讨》、上海市科委项目《上海市男性生殖与泌尿疾病药物非临床评价专业技术服务平台》;担任科技部重大新药创制科技重大专项《建立符合国际新药研究规范的临床前安全评价技术平台》课题副组长,负责《建立符合国际规范的临床前安全性评价管理和应用系统》内容建设;作为核心成员(排名前3)参与省部级课题10项,主持上述项目中所涉及前列腺增生内容研究工作,包括体内外模型建立、方法学验证和机制探讨等;专题负责完成28个药品逾60个项目的安全性评价;主持完成逾16个抗前列腺增生药物药效学研究。

 曾获RASS奖学金至德国参加国际毒理学联合会(IUTOX)主办的第11届危险性评价夏季学校学习;列入2013年上海市人才发展资金资助计划,获上海市科学技术进步二等奖(排名第三,项目名称《前列腺增生药理毒理学研究及其应用》)、上海市科学技术进步三等奖(排名第二,项目名称《宫颈糜烂防治技术与产品开发》)、华夏医学科学技术奖二等奖(排名第二,项目名称《抗前列腺疾病药物非临床评价体系的建立和应用》)、中国实验动物学会科学技术奖二等奖(排名第三,项目名称《前列腺疾病生物学模型的建立和应用》)、中国药学会科学技术奖三等奖(排名第二,项目名称《男性生殖与泌尿疾病药物非临床评价体系的建立和应用》)、国际毒理学联合会CTDC高级科学家旅行奖、首届中国毒理学会优秀青年科技人才奖等奖项;作为主要发明人,已申请4项科技发明专利,获授权2项,取得一项软件著作权证书;已发表论文一百余篇,其中收录SCI论文20篇,中文核心期刊50篇;参编《前列腺药理学》等学术专著4部。

担任国家食品药品监督管理总局药品审评中心专家,国家自然基金通讯评审专家,中国毒理学会青年委员会常务委员,世界中医药学联合会临床科研统计学专业委员会理事,中国毒理学会毒理研究质量保证专业委员会委员,中国药理学会生殖药理专业委员会委员,中国环境诱变剂学会致畸委员会委员,中国毒理学会替代法与转化毒理学专业委员会, 中国药学会药物安全评价研究专业委员会委员,上海市药理学会毒理专业委员会委员,上海市实验动物学会实验动物伦理福利委员会委员,上海市实验动物学会实验动物产业化专业委员会委员, 上海市计划生育科学研究所实验动物伦理委员会委员,《中国实验动物学报》和《中国比较医学杂志》特约审稿人,《中国毒理学通讯》特约通讯员等学术职务。



Name:WU Jianhui,Ph.D., Professor.


Tel:021-64438949


E-mail:wujh_731@163.com,wujh@hotmail.com


Research field:  Prostatic Pharmcology and Toxicology, Male Reproductive Healthy Study, Preclinic Safety Envaluation on New Drugs


Introduction:

WU Jianhui, male, Han people, CPC member, born in Xingan county, Jiangxi province, on July 31st, 1976.  Ph.D. of Fudan university, professor, graduate tutor of Fudan University. Now, act as the deputy director and Party branch secretary of National evaluation center for the toxicology of fertility regulating drugs. Research mainly focus on pharmacology & toxicology study on drugs against disease of prostate, male reproductive health and non-clinical safety evaluation on new drugs, especially on the mechanism research and medicine developing of BPH.As PI, responsible for more than 3 research projects, which including one grant from National Natural Science Foundation of China. Mainly participated in one project of great program “significant novel drug innovation” from the Ministry of Science & Technology of China, two project of Shanghai public service platform of research & development, three projects of Shanghai Science & Technology innovation plan of experimental animals , one project of Shanghai Qimingxin program foundation, one project of Shanghai program foundation of tackle key problems in science and technology and three projects of Shanghai great project program foundation. As a study director,  responsible for more than 60 items’ of 28 drugs’ safety assessment studies. Responsible for more than 16 pharmacodynamics studies of anti-benign prostatic hyperplasia drugs, and further studied some phenomena that met during working and published related papers.

Once won the RASS fellowship of International Union of Toxicology (IUTOX) and took part in the eleventh risk assessment summer school (RASS XI) of IUTOX in Germany in 2006. Won the support of Shanghai talent development fund in 2013, Second-grade award of Shanghai Science &Technology progress in 2004, outstanding paper of young scientists in the 9th National Congress of Chinese Herb Pharmacology in 2005, outstanding young scientist of Chinese Society of Toxicology in 2007, outstanding paper of young scientists in the 5th National Congress of Chinese Society of Toxicology in 2009, Second-grade award of Dahua outstanding young scientist of Shanghai institute of planned parenthood research in 2010, third-grade award of Shanghai Science &Technology progress in 2011, second-grade award of Science & Technology of Chinese Association For Laboratory Animal Sciences in 2012, third-grade award of Science & Technology of Chinese Pharmaceutical Association 2013, second-grade award of Science & Technology of the chinese medical care for the international exchange in 2014,et al . Published more than 100 papers, including 20 SCI papers and articleOral exposure to low-dose bisphenol A aggravates testosterone-induced benign hyperplasia prostate in rats, applied for 4 patents and published 4 books.

Now is the Member of Youth Committee of CST (Chinese Society of Toxicology), Council Member of the 1st Board of Specialty Committee of Clinical Scientific Research Statistics of World Federation of Chinese Medicine Societies, member of Toxicology Research Quality Assure Committee of CST, Member of Reproductive Pharmacology Committee of Chinese Pharmacology Society, Member of Teratogenicity Committee of Chinese Enviromental Mutagen Society, Member of Drug Safety Evaluation  Committee of Chinese Pharmaceutical Association,  Member of Animal Welfare& Ethic Committee of Shanghai Association For Laboratory Animal Sciences, Member of Toxicology Committee of Shanghai Pharmacology Society, et al.


 

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